Jack Muldoon's brace, plus strikes by Lloyd Kerry and Aaron Martin sunk the Shrimpers and took Simon Weaver's men to the top of the League two standings on the opening day of 2020/21.
Here's a selection of images from Saturday's clash at Roots Hall. PICTURES: GETTY IMAGES.
1. Southend United v Harrogate Town
Harrogate Town played their first-ever Football League game at Southend United's Roots Hall on Saturday afternoon. Pictures: Getty Images
2. Southend United v Harrogate Town
Jack Muldoon struck on 25 minutes to give Town the lead.
3. Southend United v Harrogate Town
Lloyd Kerry jumps for joy after doubling the visitors' advantage just before half-time.
4. Southend United v Harrogate Town
Lloyd Kerry gives the Harrogate bench a thumbs up having bagged his team's second of the afternoon.