Work is due to start this month on constructing a new roundabout on the A61 to provide access for the 124-bed care home in Pannal.
The developer, Forward Investment LLP, will start work on April 25 constructing the roundabout as part of plans to redevelop the former Dunlopillo factory.
Plans to build 120 houses, light industrial units and a park and ride facility were approved in March 2013 but the developers reapplied to include a care home on the site.
As part of the plans, the developers pledged to build a new roundabout and access road for the care home on the A61 in Pannal with construction work lasting for 26 weeks.
The work is estimated to finish in October with the care home, which is currently being built, due to open the following month.
The majority of the work is due to be constructed off lined meaning motorists should be inconvenienced for the entire six-and-a-half months.
However, traffic is believed to be interrupted for three weeks in September with the final phase of work involving traffic light control working and possibly an overnight closure.
Pannal residents are due to receive letters from the contractor AE Yates regarding the works with a public meeting planned for the village hall on April 19.
The state-of-the-art care home is due to provide dementia care in eight specialist care areas within one. The home will provide 124 en-suite bedrooms managed in 8 local care clusters to provide personal care.
The site was once occupied by a major mattress manufacturer, Dunlopillo, but went into administration in 2008 resulting in the loss of 155 jobs.